Effect of supplementation in treatment of patients with multiple sclerosis
Phase 2
Completed
- Conditions
- Multiple sclerosis.Multiple sclerosis
- Registration Number
- IRCT201511015623N59
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Ages between 18 and 55
The course of RRMS diagnosed according to McDonald criteria
EDSS score =4.5
Exclusion Criteria
Women who were pregnant
Lactating during the past six months
Nephrolithiasis for the past 5 years
Menopaused women with irregular menstruation
Unwillingness to utilize appropriate contraceptive tools.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method EDSS. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Physical Examination by Neurologist.;High-sensitivity C-reactive protein. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie probiotic effects on metabolic profiles in multiple sclerosis patients?
How does probiotic supplementation compare to standard-of-care treatments for relapsing-remitting multiple sclerosis?
Which biomarkers correlate with metabolic profile changes in IRCT201511015623N59 MS trial?
What adverse events are associated with probiotic interventions in neuroinflammatory diseases?
Are there synergistic effects of combining probiotics with immunomodulatory therapies in multiple sclerosis?