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Clinical Trials/NL-OMON44064
NL-OMON44064
Completed
N/A

Advanced Image Supported Lef ventricular Lead Placement in Cardiac Resynchronization Therapy - Advise-CRT

niversitair Medisch Centrum Utrecht0 sites15 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
cardiac decompensation
Sponsor
niversitair Medisch Centrum Utrecht
Enrollment
15
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
niversitair Medisch Centrum Utrecht

Eligibility Criteria

Inclusion Criteria

  • An indication Cardiac Resynchronization Therapy according to the current international evidence based guidelines for CRT (the 2013 European Society of Cardiology Guidelines for cardiac pacing and cardiac resynchronization therapy):
  • \-Chronic heart failure;
  • \-New York Heart Association functional class II, III, IV (ambulatory);
  • \-QRS duration \*120ms;
  • \-Optimal pharmacological therapy;
  • \-Left ventricular ejection fraction \*35%;;And specifically for phase 1 of the study:
  • \-Documented history of myocardial infarction, coronary artery disease, or delayed enhancement on a prior MRI.

Exclusion Criteria

  • \-Contraindications for implantation of a CRT device;
  • \-Age \<18 years or incapacitated adult;
  • \-Pregnancy; if there is anamnestic doubt regarding postmenopausal state (\<1 year since last menstruation), an urine hCG test (Alere) will be performed.
  • \-Lactation;
  • \-Impaired renal function (severe renal insufficiency, GFR \< 30 ml/min/1\.73m2\);
  • \-Permanent atrial fibrillation or atrial fibrillation during MRI
  • \-Documented allergic reaction to gadolinium;
  • \-Documented allergic reaction to contrast agent;
  • \-Impossibility to undergo a MRI scan (determined by using the standard contraindications for MR imaging as used for clinical purposes).
  • \-Participation in another clinical study that prohibits any procedures other than standard. ;After study MRI:

Outcomes

Primary Outcomes

Not specified

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