IRCT20140818018842N29已完成2 期
Evaluation of the safety and effectiveness of Haploidentical hematopoietic stem cell transplantation for the treatment of severe aplastic anemia patients who lack an Human leukocyte antigen (HLA)-matched (sibling or unrelated) donor.
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •Patients from 18 to 60 years old
- •Patients with Severe Aplastic Anemia
- •Patients unresponsive to prior immune suppressive treatments.
- •No full matched (sibling or unrelated) donor available.
排除标准
- •Prior allogeneic stem cell transplantation
- •Symptomatic coronary artery disease
- •Karnofsky Performance Score < 60
- •Patients with uncontrolled bacterial, viral or fungal infection
- •A known life-threatening reaction (anaphylaxis) to Thymoglobin.
- •Females who are pregnant or breastfeeding.
- •Patients seropositive for human immunodeficiency virus or active hepatitis B or C with detectable viral load.
- •Received Antithymocyte globulin drug within 2 weeks before enrolling in the study.
- •Previous malignancies other than resected basal cell carcinoma or cervical cancer treated in situ.
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