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Clinical Trials/NCT05589220
NCT05589220
Recruiting
Not Applicable

Multi-method Pilot Study to Evaluate the Interest of Music Therapy Associated to Nicotine Replacement Therapy (NRT) Versus NRT Alone on Craving Related to Smoking Cessation in Students.

Poitiers University Hospital1 site in 1 country120 target enrollmentDecember 13, 2022

Overview

Phase
Not Applicable
Intervention
Music Intervention
Conditions
Smoking Cessation
Sponsor
Poitiers University Hospital
Enrollment
120
Locations
1
Primary Endpoint
Assess if Music therapy associated to NRT decrease tobacco craving compared to NRT alone
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 120 student smokers (18 to 25 years old). This pilot multi-method study will combine the methodology of clinical trials with qualitative techniques used in social sciences to show the interest of a digital music therapy tool, adapted to a young audience.

Detailed Description

The participants will be recruited at the Clinical Investigation Center (CIC) of the University Hospital of Poitiers. At baseline visit, they will be randomly 1:1 assigned to receive either music therapy and NRT or NRT alone for 3 months. During the 3 months after TQD (Target Quit Date), 3 visits will be performed by practitioners at the CIC. Practitioners will register smoking status of the participant, exhaled carbon monoxide concentration, body weight and all adverse events. Participants will answer questionnaires (FTCQ-12, HAD, MNWS, UPPS).

Registry
clinicaltrials.gov
Start Date
December 13, 2022
End Date
March 1, 2028
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • students, age \>=18 and \<=25 years,
  • smoking more than 5 cigarettes per day for at least 6 months,
  • motivated to quit smoking,
  • without legal tutors or subordination,
  • affiliated to a health insurance system as required by the French law on biomedical research,
  • written informed consent for participation in the study.

Exclusion Criteria

  • Roommates and couples,
  • NRT contraindication
  • with depression and/or psychosis and/or cognitive disorder and/or mental retardation,
  • substance misuse or alcohol dependence,
  • smoking-cessation medication (NRT, bupropion, varenicline) or undergoing cognitive-behavioral therapy or hypnotherapy in the last 3 months,
  • electronic cigarette for smoking cessation in the last 3 months,
  • Persons benefiting from enhanced protection, i.e. persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.

Arms & Interventions

Music intervention and NRT

The rhythm of the music sessions will be 2 per week in the first month, 1 per week in the second month and 1 every 15 days in the third month. In this group, music intervention will be associated to NRT.

Intervention: Music Intervention

Music intervention and NRT

The rhythm of the music sessions will be 2 per week in the first month, 1 per week in the second month and 1 every 15 days in the third month. In this group, music intervention will be associated to NRT.

Intervention: Nicotine replacement

NRT group

Nicotine Patch, Nicotine Gum As in the intervention group, the physician will adapt the type of NRT according to the patient's smoking profile.

Intervention: Nicotine replacement

Outcomes

Primary Outcomes

Assess if Music therapy associated to NRT decrease tobacco craving compared to NRT alone

Time Frame: Month 1

Score of French Version of the Tabacco Craving Questionnaire-12 (FTCQ-12). It consist of 12 questions, each rated on a likert-type scale with 7 response options. Lower scores mean a better outcome.

Secondary Outcomes

  • Test the feasability of such a program in smoking cessation(Month 3)
  • Evaluate the evolution of tobacco craving(Month [2; 3])
  • Evaluate the evolution of Anxiety(Month [1;2; 3])
  • Evaluate the evolution of nicotine withdrawal symptoms(Month [1;2; 3])
  • Evaluate the evolution of impulsivity(Month [1;2; 3])
  • Evaluate the efficacy of the intervention on smoking cessation(Month [1;2; 3])

Study Sites (1)

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