comparison between efficacy of different local anesthetics

Completed

Brief Summary: .To compare the efficacy of conventional, pre-heated and buffered local anesthetics ie. 2% Lignocaine in patients with symptomatic irreversible pulpitis on giving inferior alveolar nerve block checked on VAS scale.

To compare pain on injection between conventional, pre-heated and buffered local anaesthetic ie. 2% Lignocaine in patients with symptomatic irreversible pulpitis on Administrating inferior alveolar nerve block checked on VAS scale on mandibular posterior teeth.

The main purpose of study is to evaluate the pain pre and post operatively following an Endodontic access cavity preparation.

Recruitment & Eligibility

Inclusion Criteria

Both male and female patients between 18-60 years of age will be included in the study.
Patients diagnosed with symptomatic irreversible pulpitis with or without apical periodontitis.
Patient should have actively experienced moderate to severe pain pre operatively on VAS scale.32 4.
A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.
Patients diagnosed with symptomatic irreversible pulpitis in mandibular molar teeth will be included in study.

Exclusion Criteria

Patients allergic to local anesthetics or known allergy to sodium bicarbonates will be excluded from study.
Pregnant and lactating patients will be excluded from study.
Patients taking any analgesics, antibiotics, sedatives, and antianxiety drugs on regular basis or before 24 hrs.
of treatment will be excluded.
Patient having history of significant medical condition will be excluded from study.
Patient having necrosed tooth with sinus tracts/local gum swelling around the affected tooth.
Patients with severe periodontitis and poor oral hygiene.

Primary Outcome Measures

Name	Time	Method
1.To evaluate the efficacy of preheated local anaesthetic ie. 2% Lignocaine in patient with symptomatic irreversible pulpitis on giving inferior alveolar nerve block checked on VAS scale. 2.To evaluate efficacy of buffered local anaesthetic ie.2% Lignocaine on VAS scale.3.To evaluate efficacy of conventional local anaesthetic ie. 2% Lignocaine checked on VAS scale.4.To compare the efficacy of conventional, pre-heated and buffered local anesthetics ie. 2% Lignocaine checked on VAS scale.	pre and post operatively

Secondary Outcome Measures

Name	Time	Method
To compare pain on injection between conventional, pre-heated and buffered local anaesthetic ie. 2% Lignocaine in patients with symptomatic irreversible pulpitis on Administrating inferior alveolar nerve block checked on VAS scale on mandibular posterior teeth.	after inferior alveolar nerve block

Locations (1): K M Shah Dental College and Hospita
🇮🇳
Vadodara, GUJARAT, India
K M Shah Dental College and Hospita
🇮🇳Vadodara, GUJARAT, India
Dr Namita Gandhi
Principal investigator
9922470078
namitagandhi95@gmail.com