CTRI/2022/09/045630招募中不适用
A comparative study of 2% lignocaine nebulization with 0.5% ropivacaine nebulization for attenuation of haemodynamic responses to endotracheal intubation and extubation
Goa Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2022年9月20日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- To compare the efficacy of 2% lignocaine with 0.5% ropivacaine 5ml nebulization ,in attenuation of haemodynamic responses during endotracheal intubation and extubation
研究概览
简要总结
The purpose of this study is to evaluate the effectiveness of local anesthetic nebulization for attenuation of haemodynamic responses during endotracheal intubation and and extubation and to enhance the quality of clinical care during these procedures
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I and II patients.
排除标准
- •1.Patient Refusal 2.Obstetric patients 3.Known allergy to drugs involved in the study 4.Patients with clinical evidence of difficult airway 5.Emergency surgical procedures with full stomach requiring RSI.
结局指标
主要结局
To compare the efficacy of 2% lignocaine with 0.5% ropivacaine 5ml nebulization ,in attenuation of haemodynamic responses during endotracheal intubation and extubation
时间窗: At Baseline | Before Laryngoscopy and intubation | Immediately after Laryngoscopy and intubation | Every 1 minute for next 5 minutes | 10 minutes after intubation | Upon anaesthetic withdrawal | Upon eye opening on verbal command | Upon tracheal extubation | Two minutes after extubation
次要结局
- To evaluate cough response and haemodynamics during extubation with airway topicalization(severity of cough and haemodynamic parameters at the time of extubation are studied)
研究者
研究点 (1)
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