A comparative study of 2% lignocaine nebulization with 0.5% ropivacaine nebulization for controlling blood pressure and heart rate during intubation and extubation after general anaesthesia

Recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/09/045630
• Lead Sponsor: Goa Medical College and Hospital

Brief Summary

The purpose of this study is to evaluate the effectiveness of local anesthetic nebulization for attenuation of haemodynamic responses during endotracheal intubation and and extubation and to enhance the quality of clinical care during these procedures

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-20
• Last Update Posted: 2023-10-03

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

ASA grade I and II patients.

Exclusion Criteria

1.Patient Refusal 2.Obstetric patients 3.Known allergy to drugs involved in the study 4.Patients with clinical evidence of difficult airway 5.Emergency surgical procedures with full stomach requiring RSI.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of 2% lignocaine with 0.5% ropivacaine 5ml nebulization ,in attenuation of haemodynamic responses during endotracheal intubation and extubation	At Baseline | Before Laryngoscopy and intubation | Immediately after Laryngoscopy and intubation | Every 1 minute for next 5 minutes | 10 minutes after intubation | Upon anaesthetic withdrawal | Upon eye opening on verbal command | Upon tracheal extubation | Two minutes after extubation

Secondary Outcome Measures

Name	Time	Method
To evaluate cough response and haemodynamics during extubation with airway topicalization	severity of cough and haemodynamic parameters at the time of extubation are studied

Trial Locations

Locations (1)

Goa Medical College and Hospital, Operation Theatre(Lower and Upper OT); 🇮🇳 Goa, GOA, India

Goa Medical College and Hospital, Operation Theatre(Lower and Upper OT)

🇮🇳Goa, GOA, India

Balasai Gorrela

Principal investigator

8885886619

balasaig1@gmail.com