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Cerebellar stimulation to treat refractory epilepsy in childre

Phase 2
Recruiting
Conditions
refractory epilepsy
10039911
Registration Number
NL-OMON55396
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
9
Inclusion Criteria

* Refractory epilepsy for at least one year, with a seizure frequency of at
least four
per month.
* Failure of at least three adequately tried AED regimens, including ketogenic
diet if
appropriate.
* Age 4 - 18 years at time of inclusion (first 3 patients 7 - 18 years old)

Exclusion Criteria

* Other progressive neurologic or medical diseases, including lesions on
radioimaging
* Evident co-existing non-epileptic seizures
* Candidate for epilepsy surgery

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>- Amount and severity of epilepsy</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>- Cognition corrected for age combined with assesment of behavior, development,<br /><br>daily life functioning and attention<br /><br>- EEG parameters<br /><br>- adverse events</p><br>
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