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Clinical Trials/NCT04047810
NCT04047810
Completed
Phase 1

A Pilot Study to Evaluate the Safety and Feasibility of Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD)

Mayo Clinic1 site in 1 country15 target enrollmentJanuary 6, 2020
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ConditionsChronic Obstructive Pulmonary Disease
InterventionsMesenchymal Stem Cells
DrugsMesenchymal Stem Cells

Overview

Phase
Phase 1
Intervention
Mesenchymal Stem Cells
Conditions
Chronic Obstructive Pulmonary Disease
Sponsor
Mayo Clinic
Enrollment
15
Locations
1
Primary Endpoint
Adverse Events
Status
Completed
Last Updated
5 months ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

Researchers are trying to understand the effects of mesenchymal stem cells therapy in subjects with advance chronic obstructive pulmonary disease

Registry
clinicaltrials.gov
Start Date
January 6, 2020
End Date
August 15, 2025
Last Updated
5 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jorge M Mallea

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Arms & Interventions

Subjects with Advanced Chronic Obstructive Pulmonary Disease

Subjects diagnosed with severe or very severe COPD will be infused intravenously with Mesenchymal Stem Cells (MSC)

Intervention: Mesenchymal Stem Cells

Outcomes

Primary Outcomes

Adverse Events

Time Frame: One hour post completion of infusion

Number of subjects to tolerate IV infusion of Mesenchymal Stem Cells (MSC) without acute clinical or physiological deterioration

Study Sites (1)

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