Antithrombotic strategies for treatment of patients with ventricular thrombus after myocardial infarction and association of outcomes: a retrospective analysis

• Conditions: I51.3; I21; Intracardiac thrombosis, not elsewhere classified; Acute myocardial infarction

• Registration Number: DRKS00032548
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Age = 18 years
- Myocardial infarction (STEMI or NSTEMI) with PCI prior to diagnosis of the ventricular thrombus and within the same hospitalization
- Ventricular thrombus confirmed by TTE and/or cardiac MR
- Initiation of oral anticoagulation treatment

Exclusion Criteria

- Patients with anticoagulation therapies other than DOAC or Marcumar

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
• Incidence of patients with left ventricular thrombus after myocardial infarction<br>• Prescribed antithrombotic therapy<br>• Change of size and thrombus modification of ventricular thrombi under oral anticoagulation therapy with DOACs or Marcumar based on a follow-up examination with TTE or cardiac MRI in the first 3 to 6 months from baseline<br>

Secondary Outcome Measures

Name	Time	Method
Clinical outcomes:<br>• Documented/reported embolic events (stroke, myocardial infarction) <br>• Documented/reported bleeding events <br>• Documented/reported death<br>during the first 12 months after diagnostic confirmation of the ventricular thrombus and initiation of anticoagulation<br>