What is the optimal blood thinner strategy in patients with atrial fibrillation presenting with a heart attack?

Phase 1

• Conditions: Acute coronary syndrome in patients with known or new atrial fibrillation with indication for oral anticoagulants; Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]

• Registration Number: EUCTR2019-004805-28-NL
• Lead Sponsor: St. Antonius Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-10
• Last Update Posted: 29 June 2020

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 2500

Inclusion Criteria

Over 18 years of age
Acute coronary syndrome with elevated cardiac enzymes
Atrial fibrillation with long-term indication for oral anticoagulation
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 1000
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 1500

Exclusion Criteria

Severe bleeding in past 3 months
Known coagulopathy
Contra-indications for intended medication (NOAC, P2Y12-remmer, ASA)
eGFR < 15 min/kg/1.73m2

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified