Serratus Plane Block For Breast Reduction Surgery

Phase 4

Completed

• Conditions: Pain Management
• Interventions: Drug: Saline; Drug: Bupivacaine

• Registration Number: NCT02930733
• Lead Sponsor: Ataturk University

Brief Summary

Serratus plane block was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves. And this block provides sufficient analgesia lateral anterior and posterior part of thoracic wall.Increased use of ultrasound guidance for regional anesthesia in recent years has led to definition of thoracic wall PECs blocks by Blanco. The Serratus plain block (SPB), providing wider analgesia, with easier application and less adverse effects than neuroaxial blocks, has been defined after these blocks and has taken its place in the literature.In spite of the insufficient randomized clinical trials in the literature, SPB has been reported for many cases such as thoracoscopy, shoulder arthroscopy, breast surgery and axillary lymph node dissections, and the results are promising. The aim of this study is to determine effectiveness of ultrasound guided bilateral serratus plane block in patients undergoing breast reduction surgery.

Main outcome measures: The primary endpoint is postoperative opioid consumption.

Secondary endpoints are visual analogue pain scores, opioid related side effects.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07
• Study First Submitted: 2016-10-10
• Study First Submitted QC: 2016-10-11
• Study First Posted: 2016-10-12
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-21
• Last Update Posted: 2017-01-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• American Society of Anesthesiologist's physiologic state I-III patients undergoing breast reduction surgery

Exclusion Criteria

• chronic pain
• bleeding disorders
• renal or hepatic insufficiency
• patients on chronic non-steroidal anti-inflammatory medications
• emergency cases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ultrasound guided sham block	Saline	Bilateral ultrasound guided sham block with 2 ml saline subcutaneously
ultrasound guided serratus plane block	Bupivacaine	Bilateral ultrasound guided serratus plane block with 30 ml %0,25 bupivacaine

Primary Outcome Measures

Name	Time	Method
Opioid Consumption	First 24 hours total opioid consumption	First 24 hours total fentanyl consumption with patient controlled analgesia

Secondary Outcome Measures

Name	Time	Method
Visual analog pain score	postoperative 24th hour	Post operative pain will be evaluated with a Visual Analogue Scale (VAS) score of 0-10 (0= no pain and 10= worst imaginable pain) at 24th hour postoperatively.

Trial Locations

Locations (1)

Ataturk University; 🇹🇷 Erzurum, Turkey