Bupivacaine

Generic Name
Bupivacaine
Brand Names
Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
Drug Type
Small Molecule
Chemical Formula
C18H28N2O
CAS Number
38396-39-3
Unique Ingredient Identifier
Y8335394RO
Background

Bupivacaine is a widely used local anesthetic agent.

Indication

As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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Associated Conditions
Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
Associated Therapies
General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Clinical Trials
Related News

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First Posted Date
2024-12-20
Last Posted Date
2024-12-20
Lead Sponsor
Assiut University
Target Recruit Count
63
Registration Number
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Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery

First Posted Date
2024-11-26
Last Posted Date
2024-12-17
Lead Sponsor
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Target Recruit Count
132
Registration Number
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Locations
🇨🇳

Jiangling Wang, Hangzhou, Zhejiang, China

Effect of Adding Magnesium Sulphate As Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal Plane Block in Upper Abdominal Cancer Surgery.to Assess the Total Postoperative Opioid Consumption in the First 24 H and Evaluate Post Operative VAS Score

First Posted Date
2024-11-07
Last Posted Date
2024-11-07
Lead Sponsor
Assiut University
Target Recruit Count
68
Registration Number
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Effect of Bupivacaine Liposomes or Bupivacaine for Femoral Triangle or Adductor Block on Analgesia After Total Knee Replacement

First Posted Date
2024-10-22
Last Posted Date
2024-10-24
Lead Sponsor
Huazhong University of Science and Technology
Target Recruit Count
144
Registration Number
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Locations
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Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

First Posted Date
2024-10-14
Last Posted Date
2024-10-14
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Target Recruit Count
70
Registration Number
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Locations
🇪🇬

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Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

Phase 2
Not yet recruiting
Conditions
Nephrolithiasis
Interventions
Other: Normal saline
Drug: Bupivacaine
First Posted Date
2024-10-10
Last Posted Date
2024-11-13
Lead Sponsor
University of Chicago
Target Recruit Count
116
Registration Number
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Locations
🇺🇸

The University of Chicago Medical Center, Chicago, Illinois, United States

EXPAREL IPSA Block in Knee Arthroplasty

First Posted Date
2024-09-30
Last Posted Date
2024-09-30
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Campbell Clinic
Target Recruit Count
10
Registration Number
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Locations
🇺🇸

Campbell Clinic, Germantown, Tennessee, United States

The Effect of Intraperitoneal Instillation of Bupivacaine on Postoperative Pain After Surgical Laparoscopy

Phase 3
Completed
Conditions
Post Operative Pain
Interventions
Drug: Bupivacaine
First Posted Date
2024-09-27
Last Posted Date
2024-09-27
Lead Sponsor
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Target Recruit Count
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Pain Palliation in Forearm Fractures in the Emergency Department

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Last Posted Date
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78
Registration Number
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Locations
🇹🇷

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Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis

First Posted Date
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Last Posted Date
2024-08-29
Lead Sponsor
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Target Recruit Count
60
Registration Number
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Locations
🇺🇸

Texas Childrens Hospital Pavilion for Women, Houston, Texas, United States

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