The Effects of Bilateral Serratus Plane Block on Postoperative Opioid Consumption After Breast Reduction Surgery
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Opioid Consumption
研究概览
简要总结
Serratus plane block was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves. And this block provides sufficient analgesia lateral anterior and posterior part of thoracic wall.Increased use of ultrasound guidance for regional anesthesia in recent years has led to definition of thoracic wall PECs blocks by Blanco. The Serratus plain block (SPB), providing wider analgesia, with easier application and less adverse effects than neuroaxial blocks, has been defined after these blocks and has taken its place in the literature.In spite of the insufficient randomized clinical trials in the literature, SPB has been reported for many cases such as thoracoscopy, shoulder arthroscopy, breast surgery and axillary lymph node dissections, and the results are promising. The aim of this study is to determine effectiveness of ultrasound guided bilateral serratus plane block in patients undergoing breast reduction surgery.
Main outcome measures: The primary endpoint is postoperative opioid consumption.
Secondary endpoints are visual analogue pain scores, opioid related side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologist's physiologic state I-III patients undergoing breast reduction surgery
排除标准
- •chronic pain
- •bleeding disorders
- •renal or hepatic insufficiency
- •patients on chronic non-steroidal anti-inflammatory medications
- •emergency cases
研究组 & 干预措施
ultrasound guided serratus plane block
Bilateral ultrasound guided serratus plane block with 30 ml %0,25 bupivacaine
干预措施: Bupivacaine (Drug)
ultrasound guided sham block
Bilateral ultrasound guided sham block with 2 ml saline subcutaneously
干预措施: Saline (Drug)
结局指标
主要结局
Opioid Consumption
时间窗: First 24 hours total opioid consumption
First 24 hours total fentanyl consumption with patient controlled analgesia
次要结局
- Visual analog pain score(postoperative 24th hour)