Verbesserung Kognitiver Fähigkeiten im Alter
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 2
- 主要终点
- Neuropsychological Performance in Neuropsychological Test: Verbal Learning Memory Test (VLMT)
研究概览
简要总结
This study investigates the beneficial effects of prefrontal brain stimulation (with transcranial direct current stimulation [tDCS]) during working memory training in seniors with subjective memory impairments.The placebo-controlled double blinded study includes 50 elderly probands which were randomized into verum or sham tDCS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •native german speaker
- •between 60-70 years old
- •subjective memory impairment
排除标准
- •psychiatric, neurological diseases
- •uncorrected hearing or vision deficits
- •actual psychopharmaco intake
- •metal parts in the head
- •medical electronical implants
研究组 & 干预措施
Verum tDCS
Left frontal anodal stimulation, supraorbital right cathodal stimulation
干预措施: Verum tDCS (Device)
Sham tDCS
sham stimulation, same electrode positions
干预措施: Sham tDCS (Device)
结局指标
主要结局
Neuropsychological Performance in Neuropsychological Test: Verbal Learning Memory Test (VLMT)
时间窗: 4 weeks
The Investigators are measuring cognitive performance for different executive functions, here the score (percentile of the norm values) of the test verbal learning memory test (VLMT), parameter immediate recall post treatment is reported. Rage from 0 to 100 %. Higher values indicate higher performance.
次要结局
- Brain Activation Measured With Near-infrared Spectroscopy (NIRS) During the Semantic Condition of the Verbal Fluency Task (VFT)(4 weeks)