Effect of Intravenous Dexmedetomidine infusion on total duration of analgesia in patients receiving intrathecal hyperbaric levobupivacaine in lower limb surgeries: Randomized Controlled trial.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare sensory and motor nerve block characteristics (onset, duration and recovery) in both
研究概览
简要总结
There are very few studies showing effect of IV Dexmedetomidine on sensory and motor block
characteristics. Further research is warranted to determine optimal dosing, timing, and patient characteristics
that maximize benefits.
As opioid sparing technique have become popular , we planned to conduct a study in patients receiving
intrathecal levobupivacaine for elective lower limb surgeries with or without use of intravenous infusion of
dexmedetomidine. We will evaluate efficacy and safety of intravenous dexmedetomidine on duration of
effective analgesia. In our study we will compare onset, duration, recovery of sensory and motor block,
hemodynamic parameters as well as perioperative complications
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with age 20 to 60 yrs ; All genders ; ASA Grading I , II ; Elective lower limb surgeries under spinal anaesthesia.
排除标准
- •Patient refusing to spinal block , pregnants , uncontrolled disease ,spine trauma.
结局指标
主要结局
To compare sensory and motor nerve block characteristics (onset, duration and recovery) in both
时间窗: 3min time interval at starting 30min then 5min for next 30min and then 15min
groups.
时间窗: 3min time interval at starting 30min then 5min for next 30min and then 15min
次要结局
- To assess hemodynamic parameters in perioperative period.(To monitor and treat the complications in perioperative period.)
研究者
DrSimran Jakhar
Adesh Institute of Medical Sciences and Research