ntargeted metabolomics and its association with intestinal microbiota metagenomics in diabetes mellitus with acute myocardial infarction (DM-AMI) patients with different
- Conditions
- Diabetes mellitus,Acute myocardial infarction
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
?The diagnosis of type 2 diabetes conforms to the diagnostic criteria of Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition);
?Acute myocardial infarction diagnosis consistents with Guidelines for rapid Emergency Diagnosis and Treatment of Acute coronary syndrome (2019);
?Blood stasis syndrome of coronary heart disease score =19 points;
?Age =18 years old,irrespective of gender;
?Volunteer for this study, sign informed consent and with good patient compliance.
?Acute complications of diabetes mellitus;
?Severe cerebrovascular disease, secondary hypertension, uncontrolled severe hypertension grade 3;
?Patients with hepatic and renal insufficiency of the progress period,malignant tumor, trauma and surgical history in recent months;
?Autoimmune diseases ,or associated with other diseases that affect glucose metabolism such as hyperthyroidism, acromegaly, and Cushing's syndrome;
?Other stress conditions combined with infection, inflammation, autoimmune diseases;
?Participated in other clinical investigators within the last 3 months;
?Pregnant and lactating women;
?Other conditions that the investigator considers inappropriate for participation in this clinical study;
?Severe mental illness.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ntargeted metabolomics;
- Secondary Outcome Measures
Name Time Method Exosomes;Intestinal microbiota metagenomics;