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临床试验/NCT04484662
NCT04484662Unknown不适用

Effects of Potted Mint Plants on Indoor Air Quality and the Concentration of Bacterium and Fungus, and Evaluation of Cardiovascular Health

National Taiwan University Hospital2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年11月9日最近更新:
适应症

试验速览

阶段
不适用
入组人数
60
试验地点
2
主要终点
Improve Indoor Air Quality

研究概览

简要总结

This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). We will apply Kore Technology (MS-200) (Electron Ionization time-of-flight mass spectrometry, EI-TOF-MS) to measure the indoor volatile organic chemicals (VOCs) before intervention and perform repeated measurements of VOCs and the concentration of phytoncides before intervention and one week later after placing potted plants into indoor environments (living room and bedroom).

In conclusion, this study aims to investigate the clinical utility of potted mint plants in reducing indoor bacterial and fungal growth and indoor air pollution, and cardiovascular benefits. Furthermore, the possible application of indoor potted mint plant in antiviral influenza or pneumonia in the future.

详细描述

The contribution of air pollution is a very important public health issue for human health. Indoor air quality may have more influence on human health than outdoor air pollution. Previous studies indicate indoor air pollution which causes respiratory disease has been associated with cardiovascular disease. Besides, some studies showed that indoor CO2 concentration was positively correlated with virus detection and bacterial concentration in the air, and coagulase-negative staphylococci (CNS) was detected in many poorly ventilated indoor environments. Mint can release chemical substance to inhibit viruses and bacteria. Among the components, the menthol and terpineol induced vasodilation so as to reduce blood pressure. For the pilot study we have finished the qualitative and quantitative research in chemical components released by the mint.

Therefore, this study aims to evaluate the indoor air quality and the distribution of fungal and bacterial concentration in the indoor environment, analyze the effect of potted mint plants on indoor air quality, fungal and bacterial concentration, and explore the correlation between the intervention of potted mint plants and cardiovascular health.

This study will recruit 60 subjects, in sum of 30 families. We will measure 2 indoor environments (living room and bedroom) for All-in-one monitoring the indoor air quality, in which collected culturable fungus and bacteria indoor to calculate colony forming unit (CFU). We will apply Kore Technology (MS-200) (Electron Ionization time-of-flight mass spectrometry, EI-TOF-MS) to measure the indoor volatile organic chemicals (VOCs) before intervention and perform repeated measurements of VOCs and the concentration of phytoncides before intervention and one week later after placing potted plants into indoor environments (living room and bedroom).

Furthermore, we used matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) to identify microbiology; simultaneously, we record the outdoor environment and indoor ventilation. To assess subjects' cardiovascular health, we use DynaPulse to evaluate their cardiovascular function, and make them equipped with Holter electrocardiography (ECG) to continuously monitor the trend of heart rate variability (HRV) before and after intervention.

In conclusion, this study aims to investigate the clinical utility of potted mint plants in reducing indoor bacterial and fungal growth and indoor air pollution, and cardiovascular benefits. Furthermore, the possible application of indoor potted mint plant in antiviral influenza or pneumonia in the future.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Health Services Research
盲法
None

盲法说明

This study will recruit 60 subjects, in sum of 30 families.

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • in the Department of Cardiology or inpatients at National Taiwan University Hospital
  • aged 20-80
  • live in the Greater Taipei area

排除标准

  • The research subjects must agree to cooperate with the health assessment.
  • serious brain, heart disease and mental illness
  • uncomfortable reactions

结局指标

主要结局

Improve Indoor Air Quality

时间窗: one week

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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