Effects of Two Systemic Drugs on Intraocular Pressure in Narrow Angle Glaucoma
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Changes in intraocular pressure (IOP) measured by applanation tonometry
研究概览
简要总结
To assess intraocular pressure changes among glaucoma patients on systemic antihypertensive and antihistaminic drugs.
详细描述
Changes in intraocular pressure in glaucomatous patients with narrow angle may elicit attacks of angle closure glaucoma.
In this study we aim to assess changes in intraocular pressure (IOP) among glaucomatous patients on systemic antihypertensive and antihistaminic drugs.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 35 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with narrow angle glaucoma on systemic antihypertensive and/or antihistaminic drugs.
排除标准
- •open angle glaucoma patients confirmed by gonioscopy examination.
- •Cases with dense corneal opacity or iris trauma that may affects gonioscopy examination.
- •cases with secondary glaucoma.
研究组 & 干预措施
Antihypertensive drugs group
Changes in IOP among patients on antihypertensive drugs
干预措施: Antihypertensive Agents (Drug)
Antihistaminic drugs group
Changes in IOP among patients on antihistaminic drugs
干预措施: Antihistaminics (Drug)
Antihypertensive and antihistaminic drugs group
Changes in IOP among patients on both antihypertensive and antihistaminic drugs
干预措施: Antihypertensive Agents (Drug)
Antihypertensive and antihistaminic drugs group
Changes in IOP among patients on both antihypertensive and antihistaminic drugs
干预措施: Antihistaminics (Drug)
结局指标
主要结局
Changes in intraocular pressure (IOP) measured by applanation tonometry
时间窗: Immediately after visual acuity assessment for each eye after topical anesthetic eye drops and again on one and three months visit
Changes in IOP measured by millimeter mercury (mmHg)
次要结局
- Changes in pupil diameter(Immediately after slit lamp examination and again on one and three months visit)
研究者
Ahmed Abdelshafy
Lecturer of Ophthalmology
Benha University