MedPath

Treatment of ectopic pregnancies of participants with vinorelbine tablets.

Phase 2
Recruiting
Conditions
ECTOPIC PREGNANCY
Reproductive Health and Childbirth - Other reproductive health and childbirth disorders
Registration Number
ACTRN12617001118392
Lead Sponsor
orth Shore Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
20
Inclusion Criteria

•Aged 18-50 years old
•English speaking
•Able to provide informed consent to participate
•A diagnosis of a tubal ectopic pregnancy on transvaginal ultrasound
•A stable ectopic pregnancy (no evidence of bleeding or rupture)
•A pre-treatment serum Human Chorionic Gonadotrophin (hCG) level of 1,000 – 3,000 IU/L
•Adnexal mass less than or equal to 3.0 cm, with no fetal cardiac activity

Exclusion Criteria

•Unable to provide informed consent to participate
•A multiple pregnancy
•Contraindication(s) to vinorelbine or to medical management of ectopic pregnancy
•Immunodeficiency disorder(s)
•A current malignancy
•Received chemotherapy or radiation therapy in the previous five years
•Concomitant disease which could significantly impair gastric absorption (Inflammatory bowel disease, coeliac, etc.)
•History of surgical resection of the stomach/small bowel
•Breastfeeding
•Hepatic impairment, renal impairment, or haematological toxicity

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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