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A Randomised Phase II study of Oral Vinorelbine or I.V. Vinorelbine in patients with metastatic breast cancer previously treated with anthracyclines

Conditions
Treatment in metastatic breast cancer previously treated with anthracyclines
Registration Number
EUCTR2004-000963-81-AT
Lead Sponsor
Robapharm AG
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Female
Target Recruitment
230
Inclusion Criteria

- Women over 65 years
- Prior therapy with anthracyclines
- Documented metastatic breast cancer
- Karnofsky Performance Status not less than 70%
- Presence of at least one measurable lesion according to RECIST criteria
- Adequate haematological, hepatic and renal function

Are the trial subjects under 18?
Number of subjects for this age range:
F.1.2 Adults (18-64 years)
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- Patients with life-threatening conditions
- Malabsorption syndrome or disease significantly affecting gastro-intestinal function or major resection of the stomach, proximal small bowel or grade not less than 2 dysphagia
- Other serious illness or medical condition

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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