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Study to assess the efficacy and safety of oral vinorelbine in combination with capecitabine in patients suffering from breast cancer previously treated with other chemotherapies (anthracyclines, and taxanes)

Phase 1
Conditions
Treatment in metastatic breast cancer women previously treated with anthracyclines and taxanes
Therapeutic area: Diseases [C] - Cancer [C04]
Registration Number
EUCTR2004-000665-35-ES
Lead Sponsor
Pierre Fabre Medicament
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Female
Target Recruitment
0
Inclusion Criteria

Women aged 18 to 75 years, documented metastatic breast disease, at least one bidimensionally measurable lesion adequately measured by imaging procedure, previously treated with anthracyclines and taxanes, Karnofsky performance status of 70 or greater, adequate haematological, hepatic and renal functions.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 45
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 45

Exclusion Criteria

Patient with poor prognosis disease, pregnant or lacting or of childbearing potential not using adequate contraception, malabsorption syndrome or disease significantly affecting gastro-intestinal function or major resection of the stomach, proximal small bowel or grade 2 or more dysphagia, other serious illness or medical conditions.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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