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A study on efficacy of autonomic nerve regulating agents on manifestation of accessory pathway in paroxysmal supraventricular tachycardia patients

Not Applicable
Conditions
Paroxysmal supraventricular tachycardia (PSVT)
Registration Number
JPRN-UMIN000030753
Lead Sponsor
Hirosaki university hospital
Brief Summary

Six patients showed fused atrial activation. Post-landiolol administration, the effective refractory period in AP stayed unchanged, while that of the AV node was prolonged. Wenckebach pacing rate via retrograde AV node decreased with landiolol, reducing the minimum ventricular pacing rate for atrial activation dissociation.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
21
Inclusion Criteria

Not provided

Exclusion Criteria

A)Patients who have allergy for landiolol. B)Patients who have contraindications for beta blocker (uncontrolled bronchial asthma, shock, coronary spastic angina, peripheral artery disease). C)Patients with heart rate of 40 times/min or less D)Patients with low left ventricular function (left ventricular ejection fraction: 25% or less). E)Patients who are not willing to participate in the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Effective refractory period of and conduction time of accessory pathway.
Secondary Outcome Measures
NameTimeMethod
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