Effects of Exercise on Multiple Risk Factors and Health Costs in Community Living Elderly Women. The Senior Fitness and Prevention Study (SEFIP)
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Atrophy
- Sponsor
- University of Erlangen-Nürnberg Medical School
- Enrollment
- 246
- Locations
- 2
- Primary Endpoint
- falls after 18 months
- Status
- Terminated
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to determine whether exercise training may impact relevant risk factors and health costs of community living women older 65 years.
Detailed Description
The human aging process is associated with a significant increase of risk factors (i.e. osteoporosis, coronary heard disease, diabetes) and a decline in neuromuscular function impacting independence of the subject. Osteoporosis, diabetes type II and arteriosclerosis are diseases known to correlate with age. Participating in regular sport activities elicits numerous favorable effects that contribute to "healthy aging". Unfortunately all existing studies which focus on specific diseases or conditions favour dedicated exercise regimes. However, the complex risk factor scenario of older adults requires multi-purpose exercise programs with impact on all relevant risks. Furthermore so far no exercise study longitudinally determines the effect of an ambulatory exercise program on health cost considering the specific health policy framework of Germany. We hypothesize that regular exercise 1. significantly impact relevant osteoporosis, cardiovascular diseases and diabetes risk factors in elderly subjects 2. significantly reduces health costs in elderly community living women
Investigators
Eligibility Criteria
Inclusion Criteria
- •Community living Caucasian woman ≥ 65 years; live expectation \> 2 years
Exclusion Criteria
- •secondary osteoporosis
- •CVD-events including stroke
- •Participation in other studies
- •Medication with impact on bone during the last 2 years:
- •bisphosphonates
- •parathormone
- •strontium
- •HRT, anabolic steroids
- •calcitonin
- •natriumflourides
Outcomes
Primary Outcomes
falls after 18 months
Time Frame: daily records, analysis after 18 months
Bone parameters after 6, 12 and 18 months
Time Frame: baseline, 6, 12, 18 month-control
health costs after 18 months
Time Frame: baseline 18 month control
Secondary Outcomes
- Functional status after 6, 12, and 18 months
- Quality of live after 12 and 18 months
- CHD- and diabetes-risk-factors (bodyfat, blood lipids, glucose, blood pressure) after 6, 12 and 18 months