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Identification of Outcome Relevant Indicators in Routine Data

Active, not recruiting
Conditions
Anesthesiological Risk Reduction
Intensive Care Risk Reduction
Registration Number
NCT04670744
Lead Sponsor
Charite University, Berlin, Germany
Brief Summary

The availability of electronic documentation systems in patient care means that large amounts of clinical routine data are available from which conclusions can be drawn for improving patient care. Compared to conventional research approaches, a data science-oriented approach offers the possibility of identifying patterns in routine data ("pattern recognition") that are relevant for patient-centered outcomes.

Numerous projects and sub-projects can be evaluated from this data set.

Detailed Description

The patterns that are relevant for patient-centered outcomes can be combinations of different parameters (e.g. vital signs, laboratory values, previous illnesses), which in themselves do not necessarily have a pathogenic effect, but in a specific combination may have a high relevance for the patient-centered outcome.

This project pursues as research goal the anesthesiological and intensive care risk reduction. To this end, the existing data sets of routine care are to be used to identify outcome-relevant patterns in order to derive recommendations for improving treatment in line with the patient's wishes. Standard Operating Procedures (SOPs) and Quality Indicators (QIs) in combination with the data of routine clinical care will be used as a basis. The approach outlined is closely linked to the development of quality-based treatment structures. In order to be able to offer medical treatment at a high level, associated processes must be known and operationalized, i.e. measurable. QIs (quality indicators) are an established instrument for measuring individual dimensions of treatment quality, and our clinic is a leading participant in this process at both national and international level (see Spies et al. Guidelines for Delirium, Analgesia and Sedation). The mapping of quality-based treatment structures as SOPs (Standard Operating Procedures) is also essential in this context (see Spies et al. SOPs in Anesthesiology and Pain Therapy, Thieme Verlag). By applying data science-based methods, this study pursues the overall goal of supporting the transfer of evidence-based findings in the form of QIs and SOPs into patient care.

Numerous projects and sub-projects can be evaluated from this data set.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
1000000
Inclusion Criteria
  • Age: 0 to 120 years
  • Gender: female, male, diverse
  • Electronically documented anesthesiological or intensive care treatment in the HIS (Hospital Information System) and PDMS (Patient Data Management System) of the Charité (Department of Anesthesiology and Intensive Care Medicine, CCM/CVK/CBF) since 2006
Exclusion Criteria

-none

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Functional status01.01.2016-31.12.2024

The functional status of the patient is measured by routine score data. The scores, which measure physical, role, and social functioning, and mobility reflect worse/better outcome depending on the score construction.

Secondary Outcome Measures
NameTimeMethod
Morbidity01.01.2016-31.12.2024

Morbidity is evaluated by International Classification of Diseases (ICD) (10th version). /Operation codes (OPS)

Mortality I01.01.2016-31.12.2024

Mortality is measured by inhouse mortality

Accounting data01.01.2016-31.12.2024

Accounting data are providid by the controlling department

Mortality II01.01.2016-31.12.2025

Mortality is measured by long-term mortality (1 year)

Trial Locations

Locations (2)

Department of Anesthesiology and Intensive Care Medicine (CCM/CVK), Charité - Universitaetsmedizin Berlin

🇩🇪

Berlin,, Berlin, Germany

Department of Anesthesiology and Intensive Care Medicine (CBF), Charité - Universitätsmedizin Berlin

🇩🇪

Berlin, Germany

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