Social Behavior in Depression
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Beijing Normal University
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Valuation of social information
- Last Updated
- 8 years ago
Overview
Brief Summary
In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.
Investigators
ma, yina
Principal Investigator
Beijing Normal University
Eligibility Criteria
Inclusion Criteria
- •Age range between 18 and 60
- •Education experience above high school
- •Score for Hamilton's Depression Scale \>=17
- •Diagnosis of depression through Scid
Exclusion Criteria
- •Undergoing electric shock treatment in 3 months
- •Excluding those who with bipolar disorder
- •Excluding those who with postpartum depression
- •Excluding those who with hysteria
Outcomes
Primary Outcomes
Valuation of social information
Time Frame: Baseline
The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.
Emotion recognition
Time Frame: Baseline
After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Cognitive flexibility
Time Frame: Baseline
Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Optimism bias
Time Frame: Baseline
Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Prosocial behavior
Time Frame: Baseline
The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Model-free & model-based tendency
Time Frame: Baseline
Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.