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临床试验/NCT04183855
NCT04183855Unknown不适用

The Relationship Between Blood Glucose and Satiety Ratings

Western University, Canada2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2020年2月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
24
试验地点
2
主要终点
changes in satiety ratings after the drink

研究概览

简要总结

Participants will be given a drink (and no drink for one of the treatments) prior to a pizza dinner. Ratings on satiety, appetite and desire to eat will be asked with the use of a questionnaire. Blood glucose will also be measured. One hour after the drink, participants will be given a pizza and can eat as much as they want. The pizza remaining will be weighed.

详细描述

Each participant will receive all three treatments on separate occasions in random order (separated by a week). The three treatments include control (no supplement), carbohydrates - protein (Generation UCAN supplement, 250ml, 10% solution) and carbohydrates alone (Mirexus PhytoSpherix, 250ml, 10% solution). Participants will report to the lab between 4-5 pm and 4 hours after their last meal on day they have not exercised. Participants will record food intake the day of the first experiment and will be asked to replicate both type and quantity for subsequent visits. Upon arrival at the lab, baseline measures (blood glucose as well as rating of satiety ratings, appetite and desire to eat (10-point visual analogue scale). Then the treatment will be given and all the aforementioned variables will be remeasured at 15, 30, 45 and 60 minutes post drink. At 65 minutes, participants will be provided with an ad libitum pizza meal. Participants will be told to eat until they are "comfortably full" (Bellissimo et al., 2008). The pizza provided will be weighed initially and once the participant is done eating and has left the lab, the remaining pizza will be weighed and recorded. The pizza will be a cheese only pizza to minimize any difference in energy intake due to the location of additional items placed on the pizza.

Participants will not be told the true purpose of this experiment, instead they will be told that the pizza meal is a reward for participating in the study. Later, at the conclusion of the study all will be debriefed.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy males and females at the age of 18-40
  • sedentary individuals

排除标准

  • exercise more than twice per week
  • does not like pizza
  • do not eat three meals a day
  • medications that affect eating patterns
  • have metabolic and gastrointestinal diseases

结局指标

主要结局

changes in satiety ratings after the drink

时间窗: 15, 30, 45, 60 min after the drink

satiety ratings will be asked with the use a 10 point visual analog scale (VAS) questionnaire, 10 being do not want to consume any more food and 1 being strong desire to consume food

Food intake

时间窗: 90 min after the drink

food intake after each treatment will be measured by weighing the left over pizza slices

次要结局

  • changes in appetite ratings after the drink(15, 30, 45, 60 min after the drink)
  • changes in blood glucose after the drink(15, 30, 45, 60 min after the drink)
  • changes in desire to eat ratings(15, 30, 45, 60 min after the drink)

研究者

发起方
Western University, Canada
申办方类型
Other
责任方
Principal Investigator
主要研究者

Peter Lemon

Principal Investigator

Western University, Canada

研究点 (2)

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