Effect of Curcumin on Migraine

Not Applicable

• Conditions: Migraine.; G43

• Registration Number: IRCT20121216011763N34
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 September 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 44

Inclusion Criteria

Aged 20-50 years
Diagnose of migraine by neurologist
willing to participate on study
Lack of severe depression and anxiety and stress
Not taking Vitamin and Antioxidant supplements (Vitamin E and C ? Selenium ? Zinc and Beta carotene)
Not having tension headaches
Not taking Anti migraine drugs
The absence of severe chronic disease such as Cancer ? Hepatitis ? pancreatitis ? diabetes ? Thyroid disorders ? Kidney and Liver disease
Having no inflammatory diseases or history of heart disease and stroke and taking anti-inflammatory drugs

Exclusion Criteria

Unwilling to participate in the study
Use of antioxidant supplements, vitamins and anti-migraine drugs
Chronic diseases and tension headaches
Indication of allergic symptoms due to curcumin supplementation
Pregnancy and lactation, or any major change in lifestyle or diet

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of migraine, migraine frequency and duration of headache. Timepoint: The beginning and the end of the study. Method of measurement: Questionnaire.

Secondary Outcome Measures

Name	Time	Method
evels of IL-6, CGRP and TAC. Timepoint: The beginning and the end of the study. Method of measurement: Laboratory method.