Sympatholytic Effect of High Thoracic Erector Spinae Plane Block
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 2
- 主要终点
- Perfusion index ratio at 10 minutes
研究概览
简要总结
The primary endpoint of this study was to identify if erector spinae plane bloock (ESPB) demonstrates any sympatholytic effect.
The secondary endpoint of this study was to compare the changes of PI value between responders and non-responders.
详细描述
The erector spinae plane block (ESPB) is a less invasive, safer, and technically easy alternative procedure to conventional neuraxial anesthetic techniques. In contrast to common neuraxial techniques such as paravertebral and epidural injections, the ESPB targets an interfascial plane which is far from the spinal cord, root, and pleura. First applied to thoracic neuropathic pain, currently ESPB is being applied to postoperative pain control and includes variable clinical situations. In the abdomen and thoracic wall, thoracic ESPB can be applied for pain control after cardiac surgery, video-assisted thoracic surgery, laparoscopic cholecystectomy, and thoracotomy. Recently, favorable postoperative pain control after lumbar spinal or lower limb surgeries has been reported with lumbar ESPB. In addition, ESPB has also been used for chronic pain conditions in the upper and lower extremities. The perfusion index (PI) is a numerical value for the ratio between pulsatile and non-pulsatile blood flow measured by a special pulse oximeter. Although the special probe for PI measurement is relatively more expensive compared with ordinary pulse oximetery probes, its benefit as a marker of peripheral perfusion and as an idex for sympathetic stimulation have increased its use progressively.
ESPB can achieve analgesic effect by blocking the ventral and doramal ramus and possibly by diffusion into paravertebral space. In constrast to lumar region, thoracic paravertebral space is very close to the sympathetic chain. Therefore, sympatholytic effect might be achieved by thoracic ESPB. No previous study has demonstrated the sympatholytic effect of ESPB.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Complex regional pain syndrome
- •Post-thoracotomy pain syndrome
- •Cervical foraminal stenosis
- •Cervical disc herniation
- •Herpes zoster
排除标准
- •Coagulation abormality
- •Previous spine surgery
- •Allergy to local anesthetics
结局指标
主要结局
Perfusion index ratio at 10 minutes
时间窗: baseline, 10minutes after ESPB
Perfusion index ratio at 10 minutes
Perfusion index changes among 4 times period
时间窗: baseline, 10minutes after ESPB, 20 minutes after ESPB, 30 minutes after ESPB
Perfusion index changes after T2 ESPB among 4 times period
Numerical rating scale changes among 3 times period
时间窗: baseline, 30 minutes after ESPB, 2 weeks after ESPB
Numerical rating scale changes among 3 times period
次要结局
未报告次要终点
研究者
Ji Hee Hong
Professor
Keimyung University Dongsan Medical Center
