Juvenile Systemic Sclerosis, a Retrospective Epidemiological Study on a French Cohort
- Conditions
- Juvenile Systemic Sclerosis
- Registration Number
- NCT06019234
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
Scleroderma is an inflammatory attack of the vessels leading to localized or multisystemic sclerosis. It is a rare autoimmune pathology in pediatrics.
The incidence in pediatrics is very low (about 4 per million according to an American) and therefore the data on the pathology very poor, especially on the therapeutic level.
The proposed immunosuppressive treatments are extrapolated from data in adults. The evolution of connectivity does not seem quite identical to the evolution of adult scleroderma, adaptation of treatments seems judicious. However, data on the evolution under therapy in children are still poor.
Complications related to the pathology, iatrogeny and diagnostic delay are the first causes of mortality from this pathology and deserve to be studied and if possible avoided.
The main hypothesis of the research being to bring together the experiences of the various reference and competence centers in France concerning the clinical presentation, management and follow-up of children with systemic sclerosis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 30
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The therapeutic response was evaluated by the EULAR DAS 28 -CRP at 6 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Service de Pédiatrie 1 - CHU de Strasbourg - France
🇫🇷Strasbourg, France