NCT06165679已完成3 期
Comparison Between the Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients Undergoing Endoscopic Urological Surgeries: A Randomized Controlled Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- Hypotension
研究概览
简要总结
Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients undergoing endoscopic urological surgeries
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 65 years old and above.
- •Both genders.
- •Patients scheduled to undergo endoscopic urological surgeries.
- •ASA I and II class.
排除标准
- •Patient refusal.
- •Known local anesthetic (LA) allergy.
- •Bleeding disorders.
- •Skin lesions or infections at site of needle insertion.
- •Hypertensive patients.
- •Patients candidate for transurethral resection of the prostate
- •ASA III and VI class
研究组 & 干预措施
Prilocaine group
Active Comparator
干预措施: Prilocaine (Drug)
Bupivacaine GROUP
Active Comparator
干预措施: Bupivacaine (Drug)
结局指标
主要结局
Hypotension
时间窗: Till 30 minutes after spinal anesthesia.
Incidence of hypotension from local anesthetic injection
次要结局
- Use of vasopressor drugs(Until the patient will have no lower limbs motor weakness assessed up to 6 hours after spinal anesthesia)
研究者
AbdElKhalik Mahmoud Shaban
Lecturer of anaesthesia
Cairo University
研究点 (1)
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