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Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients

Phase 3
Recruiting
Conditions
Hemodynamic Instability
Interventions
Registration Number
NCT06165679
Lead Sponsor
Cairo University
Brief Summary

Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients undergoing endoscopic urological surgeries

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
112
Inclusion Criteria
  • Patients aged 65 years old and above.
  • Both genders.
  • Patients scheduled to undergo endoscopic urological surgeries.
  • ASA I and II class.
Exclusion Criteria
  • Patient refusal.
  • Known local anesthetic (LA) allergy.
  • Bleeding disorders.
  • Skin lesions or infections at site of needle insertion.
  • Hypertensive patients.
  • Patients candidate for transurethral resection of the prostate
  • ASA III and VI class

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Prilocaine groupPrilocaine-
Bupivacaine GROUPBupivacaine-
Primary Outcome Measures
NameTimeMethod
HypotensionTill 30 minutes after spinal anesthesia.

Incidence of hypotension from local anesthetic injection

Secondary Outcome Measures
NameTimeMethod
Use of vasopressor drugsUntil the patient will have no lower limbs motor weakness assessed up to 6 hours after spinal anesthesia

Total doses of vasopressor drugs used for hypotension treatment

Trial Locations

Locations (1)

Kasr Alaini hospital

🇪🇬

Cairo, Egypt

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