"Pharmaceutico-clinical study of Kushthadi Churna and its ointment and their efficacy in the management of Vicharchika"
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- SOP and efficacy of Kushthadi Churna and its ointment would be established.
研究概览
简要总结
Different types and stages of eczema affect 31.6 million people in the United States, which equals more than 10% of the population.Vicharchika(Eczema) is a condition in which patches of skin become inflamed, itchy, cracked, and rough. Some types can also cause blisters. Acharyas has mentioned that, external applications form the best way to treat Kushtha. Application of dusting enters in to Romakupa and further gets absorbed through svedavahi srotas and siramukha leading to desired effects. This method of rubbing increases the skin temperature which might be hastening the pilosebaceous uptake and skin permeation of the drug in topical formulation. classical formulations also have some drawbacks which are not feasible in busy life style during this modern era. Now a days different herbal modern dosage forms are widely accepted because of its feasibility, effectiveness and also these are easy to carry. Therefore, it has been postulated to convert Kushthadi Churna into ointment form in the present work. Kushthadi Churna ointment will be prepared by khushthadi churna and will be local application in patients of Vicharchika( Eczema) to evaluate its effectiveness
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Open Label
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Patients having classical clinical features of Vicharhcika a.
- •Shyavavarnata d.
- •Bahusravah/Rukshtaka e.
- •Daha 2 Duration of the disease: Chronicity for less than 2 years, recurrent in nature and or not responding to conventional therapy.
- •3 Mild to moderate cases of eczema as per EASI.
排除标准
- •1 Age below 30 years and above 60 years.
- •2 Severe cases of eczema as per EASI.
- •3 Patients under long standing medication, suffering from systemic or linked disease.
- •4 Pregnant and lactating women.
- •5 Chronicity more than 2 years.
- •6 Patients with acute and chronic systemic and metabolic disorders.
结局指标
主要结局
SOP and efficacy of Kushthadi Churna and its ointment would be established.
时间窗: 28 days
次要结局
- This study will provide the analytical profile and shelf life of Kushthadi Churna ointment(28 days)