Efficacy of therapeutic emesis with Ikshvaku drug in Psoriasis

Not yet recruiting

Conditions: Allergic urticaria. Ayurveda Condition: EKAKUSHTHAH, (2) ICD-10 Condition: L503||Dermatographic urticaria. Ayurveda Condition: EKAKUSHTHAH,

Registration Number: CTRI/2025/06/089193

Lead Sponsor: SGT University

Brief Summary: In *Ayurveda*, skin diseases are included under the heading of *Kushtha* or *Kshudra Rogas*. Out of them *Kshudra Kushtha* is the *Eka-kushtha* which can be correlated up to certain extent with Psoriasis. It is chronic, non-infectious & common skin disease of today’s time. It is a very attention seeking problem approximately 2-3 % (125 million) population of the world suffering from the disease

***Eka-kushtha*** **may be characterized as follows**

1.       Absence of perspiration (*Asvedanam*)

2.       Extensive localization (*Mahavastu*)

3.       It resembles the scales of fish (*Matsyashakalata*). *Eka-kushtha* is curable disease but its relapsing nature causes more harassment for the patient. It is correlated to certain extent with Psoriasis.

**NEED AND SIGNIFICANCE****:**

There are many studies carried out on Vamana Karma by Madanphala and Jeemutaka but there are no studies reported on the use of Ikshvaku as a Vamaka dravya. So unexplored Vamaka dravya should be addressesd. The present study will evaluate the efficacy of Ikshvaku as a Vamaka dravya in *Eka-kushtha*.

**HYPOTHESIS****:**

Proper Vamana karma with Ikshvaku will remove *Eka-kushtha*.

H0=   Ikshvaku don’t have any effect in Eka- Kushtha

H1= Ikshvaku has significant effect in Eka-Kushtha.

**AIM**

To study the efficacy of Vamana karma using Ikshvaku in the patients of Eka-Kushtha.

**OBJECTIVES**

·         To study the effects of Ikhvaku as Vamakadravya in *Eka-kushtha*.

·         To study the reduction in the symptoms of *Eka-kushtha*.

**MATERIALS & METHODS**

· Ikshvaku seeds -whole fruit decoction with seed powder decoction(13gm seed powder)

·       Yashtimadhu Kashayam- 3 to 5 litre

·   Madhu- 40-60 gm

·   Saindhav- 10 gm

·   Cows milk- 1.5 lit- 2 lit

·         All these drugs and its raw materials will be purchased from Khari Baoli of Delhi market and the authentication and standardization will be done.

·         Fresh Vamaka Kalpa will be prepared at the time of clinical trial as the Standard Operative Procedure given in Charaka Samhita and under the guidance of guide.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

1 Patients who have scored more than 0 for Asvedanam, Mahavastu & Matsyashakalata lakshana in assessment criteria.
2 Patients having signs and symptoms of Eka-kushtha according to Charaka Samhita.
3 Age group from 20 to 60 yrs.
4 Patient of either sex.
5 Vamanarha patients.

Exclusion Criteria

•Patients with complications like Cardiac problems, emphysema, carcinoma, etc.
will be excluded.
•Pregnant woman and lactating mothers will be excluded.
•The patients above 60yrs and below 18yrs will be excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief in the signs and symptoms of Eka Kushtha like matsyasakalta, aswednam etc.	4 weeks

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): SGT Ayurveda Hospital
🇮🇳
Gurgaon, HARYANA, India
SGT Ayurveda Hospital
🇮🇳Gurgaon, HARYANA, India
Dr Rajni Sharma
Principal investigator
7507373663
rajnisharma.oct@gmail.com