Randomized controlled clinical trial to evaluate the efficacy of Trikantakadi Yoga in the management of Mutrakrucchra (Urinary Tract Infection) in children
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- 1.Dysuria should be decrease
研究概览
简要总结
According to Ayurveda Mutrakrucchra is a disease of Mutravaha Strotas.Mutrakrucchra is a broad term which covers the conditions described in modern medical science as Urinary Tract Infection (UTI). The Pratyatma Lakshana of Mutrakrucchra is "Dukhena Mutra Pravrutti" means discomfort during micturation. In Mitrakrucchra, the vitiated Pitta Dosha along with Vata (mainly Apana Vayu) on reaching Basti afflicts the Mutravaha Strotas .
Mutrakrucchra is also found as a Lakshana in many diseases such as Ashmari, Mutraghata, Mutrajvriddhi, Arsha and Gulma.
The Lakshana of MUTRAKRUCCHRA in children is described by Acharya Kashyap in Vedana adhyay.
Rationale of study
Urinary tract is the third commonest site of infection in children after gut and respiratory tract, involving lower urinary tract (cystitis, urethritis) or upper urinary tract infection (pyelonephritis) or both.
About 2-8% of children develop UTI by the age of 14 years.About 1-3% boys and 3-8% girls suffer with at least one attack of symptomatic UTI by 14 Years of age.It is an important cause of morbidity and might result in renal damage often in association with vesicoureteric reflux .
Dysuria is one among the important symptoms of the lower UTI by which the patients daily activities are hampered. With the introduction of effective antibiotics, problem has been solved to some extent but the use of antibiotics have side effects, chances of re-infection and relapse even after long term therapy. Simultaneously increasing incidence of resistance and high cost of therapy are common problems. So, there is a need to find low cost, harmless and preventive drug prepared from natural resources in the management of Mutrakrucchra.
Bhav Prakash has mentioned Trikantakadi Yoga for the treatment of Mutrakrucchra in children which consists of Trikantak, Aragwadh, Darbha, Kasha, Duralabha, Parvatbheda and Haritaki.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 6.00 Year(s) 至 16.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Age group between 6 years to 16 years 2.Symptoms described in the context of Mutrakrucchra 3.Patients irrespective of their gender, religion, and economic status will be included in the study.
排除标准
- •1.Patients below 6 years and above 16 years 2.Patients with congenital abnormalities and other systemic diseases.
结局指标
主要结局
1.Dysuria should be decrease
时间窗: Baseline ,5th , 10th day
2.Burning Micturation should be decrease
时间窗: Baseline ,5th , 10th day
3.Frequent Urination should be decrease
时间窗: Baseline ,5th , 10th day
次要结局
- 1. No. of pus cells should be decrease(2.ph of urine should be decrease)