Study conducted to see the effect of Kataka Beeja Churna and Gokshura Churna in Kidney stones

Phase 2

Not yet recruiting

• Conditions: Calculus of kidney. Ayurveda Condition: MUTRAVAHASROTODUSHTIH,

• Registration Number: CTRI/2022/05/042799
• Lead Sponsor: BVVS Ayurveda Medical College and Hospital Bagalkot

Brief Summary

*Ashmari* is one of the disorders of *Mutravaha Srotas* and it is included in *Astamahagada.*

The word ‘*Ashma*’ means ‘stone’ and ‘*Ari*’ means ‘enemy’. The formation of stone which cause great pain and suffering to the body like an enemy is called *Ashmari*.

Renal Calculi are one of the most painful and common disorders of urinary tract, which are solid crystals that form from dissolved minerals in urine, caused by both environmental and metabolic problems.

Acharya Sushruta explains *Lakshanas* of *Ashmari* as pain in *Nabhi* (umbilical), *Basti* (bladder), *Sevani* (perinealraphe), and *Mehana* (penis), *Mutradharana* (obstruction in flow of urine), *Sarudhiramutra* (haematuria), *Mutravikirana* (scattering of urine), *Gomedakaprakasha* (passing of urine like *Gomeda)*, *Sasikata* (with gravels) and *Visrujati* (turbid).

The lifetime risk of kidney stone is estimated to be between 5% and 10% with reoccurrence rate as high as 50%.Renal calculi occurs in people of all parts of the world with lower time risk of 3-15% in the west 25% in Asia and 20% in India. Renal calculi are quite common and usually affects people who are between 20-60 years of age, they affect male more than female. It is estimated that renal colic affects about 10-20% of male and 3-5% female.

In India, Kidney stone Disease is prevalent, with an expectancy of 12% in total population reported to be prone to urinary stone. Of this 12%, 50% of the population is affected by renal damage, which even leads to a loss of kidneys.

Acharya Sushruta has described various medicines and surgery. Medical treatment has been advised to be undertaken in the early stage of the disease. Indication for the surgical management has mentioned along with the note of caution regarding complication.

In the context of *Ashmari Chikitsa*, Acharya Sushruta has advised that surgery to be undertaken only on failure of conservative treatment and when death becomes inevitable if not treated surgically.

Acharya Sushruta explained the use of *Gokshura* with *Madhu* and *Aviksheera* as *Anupana* in *Ashmari Chikitsa*.*Gokshura* has properties like *Ashmarihara* and *Basti Shodana*.

*Kataka* explained in Dhanvantari Nighantu *Chandanadi Varga* is taken for the study. Acharya while explaining the properties of *Kataka* states, it is *Vaariprasadana, Chedaniya Vishagna* and *Muootrashmarihara*. By going through the individual *Guna Karma* of *Kataka* it is said to be *Tridoshahara.*

The study will be carried out to evaluate the effect of *Kataka Beeja* *Churna* and *Gokshura Churna* in *Mutrashmari.*

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-05-24
• Study Start: 2022-05-28

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• 1)Patients between age group of 20-60 years of either sex.
• 2)Diagnosed patients of Mutrashmari presenting with signs and symptoms of Mutrashmari(renal calculi).
• 3)Symptomatic and asymptomatic Patients with renal calculi of size 3mm to 10mm in kidney as reported by USG Abdomen and Pelvis.

Exclusion Criteria

• 1)Patient suffering with systemic disorders like Ischemic Heart Disease, tuberculosis, diabetes mellitus, hypertension etc 2)Impacted stone.
• 3)Pregnant and lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1)Pain	4 weeks
2)Tenderness over renal angle	4 weeks
3)Dysuria	4 weeks
4)Size of Renal calculi	4 weeks

Secondary Outcome Measures

Name	Time	Method
1)Hematuria	2)Pyuria

Trial Locations

Locations (1)

BVVS Ayurved Medical College and Hospital; 🇮🇳 Bagalkot, KARNATAKA, India

BVVS Ayurved Medical College and Hospital

🇮🇳Bagalkot, KARNATAKA, India

Dr Chaitra B Naduvinamani

Principal investigator

9481727634

naduvinamanichaitra@gmail.com