Preparation of soap and cream with medicated Trinak oil and its clinical trial in skin disease.
- Conditions
- Local infection of the skin and subcutaneous tissue, unspecified. Ayurveda Condition: DADRU-KUSHTHAH,
- Registration Number
- CTRI/2023/10/058304
- Lead Sponsor
- Shri Krishna Govt Ayurvedic College and Hospital
- Brief Summary
All the skin diseases in Ayurveda have been classified in to Mahakustha and Kshudra Kustha. Dadru is one among the Kustha. Acharya Charak has included Dadru in Kshudra Kustha where as Acharya Sushruta and Acharya Vagbhata have explained under Mahakustha. It involves the clinical features like Kandu, Raga, Pidika, Mandala, Utsanna which exhibits the involvement of Kapha and Pitta dosha. In the explanation of chikitsa for Dadru, Bahhiparimarjan chikitsa is mentioned. Therefore the Trinak Taila mentioned in the Chakradutta which reduces the symptoms of Dadru is taken for study. All patients will be selected from OPD of Shri Krishna Govt Ayurvedic College and Hospital, Kurukshetra. Patients with age group between 18-65 yrs with lakshan of dadru will be selected. Patients below 18yrs and above 65 yrs of age along with long standing medicine, chronicity more than 2 yrs and associated with other skin diseases will be excluded. Maximum 20 patients are in two groups. Group A has 10 patients advised for local application of Trinak Taila and Group B has 10 patients advised for local application of ointment prepared with Trinak Taila. Follow up will be done after every 7 days during trial. After completing trial for 30 days, patients will be reassessed again every 15 days for 45 days to assess the efficacy of trial drug.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- All
- Target Recruitment
- 20
Patients with the signs and symptoms of Dadru Kushtha described in Ayurvedic texts will be selected.
Patients on auto immune suppressants, patients having medical history of unstable angina, myocardial infarction, heart failure or stroke within 3 months of study, uncontrolled DM, Impaired renal function ALT and AST>2 times of upper limit of normal, patients on prolonged steroid therapy and age less than 18 yrs and more than 65 yrs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To develop & evaluate pharmaceutical, analytical study of Soap and Cream prepared with Trinak Taila and its clinical study in Dadru Kustha Roga within one year. Duration of the treatment- 28 days | follow up- done after 14 days, 28 days and 45 days.
- Secondary Outcome Measures
Name Time Method 1.To study pharmaceutical analytical evaluation of soap prepared from Trinak Tail. 2.To study pharmaceutical analytical evaluation of cream prepared from Trinak Tail.
Trial Locations
- Locations (1)
Shri Krishna Govt Ayurvedic College and Hospital
🇮🇳Kurukshetra, HARYANA, India
Shri Krishna Govt Ayurvedic College and Hospital🇮🇳Kurukshetra, HARYANA, IndiaSeemaPrincipal investigator7973299267seemagahlyan24@gmail.com