Development, Pharmaceutical, Analytical study of soap and cream prepared with Trinak Taila as main ingredient and its clinical study in Dadru Kustha Roga
试验速览
- 阶段
- 2/3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- To develop & evaluate pharmaceutical, analytical study of Soap and Cream prepared with Trinak Taila and its clinical study in Dadru Kustha Roga within one year.
研究概览
简要总结
All the skin diseases in Ayurveda have been classified in to Mahakustha and Kshudra Kustha. Dadru is one among the Kustha. Acharya Charak has included Dadru in Kshudra Kustha where as Acharya Sushruta and Acharya Vagbhata have explained under Mahakustha. It involves the clinical features like Kandu, Raga, Pidika, Mandala, Utsanna which exhibits the involvement of Kapha and Pitta dosha. In the explanation of chikitsa for Dadru, Bahhiparimarjan chikitsa is mentioned. Therefore the Trinak Taila mentioned in the Chakradutta which reduces the symptoms of Dadru is taken for study. All patients will be selected from OPD of Shri Krishna Govt Ayurvedic College and Hospital, Kurukshetra. Patients with age group between 18-65 yrs with lakshan of dadru will be selected. Patients below 18yrs and above 65 yrs of age along with long standing medicine, chronicity more than 2 yrs and associated with other skin diseases will be excluded. Maximum 20 patients are in two groups. Group A has 10 patients advised for local application of Trinak Taila and Group B has 10 patients advised for local application of ointment prepared with Trinak Taila. Follow up will be done after every 7 days during trial. After completing trial for 30 days, patients will be reassessed again every 15 days for 45 days to assess the efficacy of trial drug.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients with the signs and symptoms of Dadru Kushtha described in Ayurvedic texts will be selected.
排除标准
- •Patients on auto immune suppressants, patients having medical history of unstable angina, myocardial infarction, heart failure or stroke within 3 months of study, uncontrolled DM, Impaired renal function ALT and AST>2 times of upper limit of normal, patients on prolonged steroid therapy and age less than 18 yrs and more than 65 yrs.
结局指标
主要结局
To develop & evaluate pharmaceutical, analytical study of Soap and Cream prepared with Trinak Taila and its clinical study in Dadru Kustha Roga within one year.
时间窗: Duration of the treatment- 28 days | follow up- done after 14 days, 28 days and 45 days.
次要结局
- 1.To study pharmaceutical analytical evaluation of soap prepared from Trinak Tail.(2.To study pharmaceutical analytical evaluation of cream prepared from Trinak Tail.)
