Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives
- Conditions
- Ocular Surface DiseaseGlaucomaGlaucoma; Drugs
- Interventions
- Diagnostic Test: Intraocular pressure (IOP)Diagnostic Test: Tear Break-up Time (TBUT)Diagnostic Test: Conjuctival HyperemiaDiagnostic Test: Schirmer TestDiagnostic Test: Visual Fields and OCT RNFL
- Registration Number
- NCT05319470
- Lead Sponsor
- Democritus University of Thrace
- Brief Summary
Primary objective of this study is to study the efficacy of travoprost without preservatives in the treatment of glaucoma patients and to monitor the ocular surface.
- Detailed Description
This is a prospective study including patients visiting the outpatient glaucoma clinic of the University General Hospital of Alexandroupolis for their standard evaluation. Study population is already under treatment with a travoprost preparation without preservatives. They will be fully informed about the procedure and the purpose of the study and a written consent will be obtained. For every patient included in the study intraocular pressure will be measured using a Goldman applanation tonometer, according to the standard way of practice at our clinic. Also, Tear Break-Up-Time (BUT), conjunctival hyperemia grading and Schirmer testing will be used to assess the ocular surface state. Visual field tests and OCT RNFL measurements will also be obtained. The above measurements will be repeated 6 months after the initial examination.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
- Patients with glaucoma treated with travoprost without preservatives.
- Co-administration of another anti-glaucoma preparation with or without preservatives, Sjogren's syndrome, poor eyelid occlusion of any etiology.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Study Group Tear Break-up Time (TBUT) 100 patients with diagnosed glaucoma receiving travoprost without preservatives Study Group Visual Fields and OCT RNFL 100 patients with diagnosed glaucoma receiving travoprost without preservatives Study Group Intraocular pressure (IOP) 100 patients with diagnosed glaucoma receiving travoprost without preservatives Study Group Schirmer Test 100 patients with diagnosed glaucoma receiving travoprost without preservatives Study Group Conjuctival Hyperemia 100 patients with diagnosed glaucoma receiving travoprost without preservatives
- Primary Outcome Measures
Name Time Method Intraocular Pressure (IOP) 6 months Intraocular pressure measurement in both eyes using the Goldman applanation tonometer.
Ocular Surface Disease 6 months Tear breakup time (TBUT), conjuctival hyperemia scoring and Schirmer testing will be used to assess the ocular surface state of the study population.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Ophthalmology, University Hospital of Alexandroupolis
🇬🇷Alexandroupolis, Evros, Greece