NCT01496573CompletedNot Applicable
Observational - CRKL Expression at the Protein Level in Rhabdomyosarcoma Tumors by Tissue Microarray (TMA)
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Children's Oncology Group
- Enrollment
- 77
- Locations
- 1
- Primary Endpoint
- CRKL expression at the protein level
Study Overview
Brief Summary
This research trial studies biomarkers in tumor tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer
Detailed Description
PRIMARY OBJECTIVES:
I. To demonstrate CRKL expression at the protein level in rhabdomyosarcoma tumors by tissue microarray (TMA).
OUTLINE:
Archived tumor tissue samples are analyzed for CRKL expression.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma specimens from the Children Oncology Group (COG) tumor microarrays (TMAs)
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
CRKL expression at the protein level
Time Frame: 1 month
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Studying Protein Expression in Tissue Samples From Younger Patients With RhabdomyosarcomaAlveolar Childhood RhabdomyosarcomaEmbryonal Childhood RhabdomyosarcomaPreviously Treated Childhood RhabdomyosarcomaPreviously Untreated Childhood RhabdomyosarcomaRecurrent Childhood RhabdomyosarcomaNCT01609803Children's Oncology Group99
Withdrawn
Not Applicable
Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid TumorChildhood Atypical Teratoid/Rhabdoid TumorRhabdoid Tumor of the KidneyNCT01453465Children's Oncology Group
Completed
Not Applicable
Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic LeukemiaB-cell Childhood Acute Lymphoblastic LeukemiaChildhood Acute Lymphoblastic Leukemia in RemissionRecurrent Childhood Acute Lymphoblastic LeukemiaNCT01540578Children's Oncology Group70
Withdrawn
Not Applicable
Studying Biomarkers in Samples From Younger Patients With Kidney CancerChildhood Kidney NeoplasmCongenital Mesoblastic NephromaRhabdoid Tumor of the KidneyClear Cell Renal Cell CarcinomaNCT01642095Children's Oncology Group
Completed
Not Applicable
Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With NeuroblastomaDisseminated NeuroblastomaLocalized Resectable NeuroblastomaLocalized Unresectable NeuroblastomaRecurrent NeuroblastomaStage 4S NeuroblastomaNCT01358617Children's Oncology Group90