Database of Transthyretin Amyloid Cardiomyopathy Cases in a Racially and Ethnically Diverse Population in the Bronx
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 476
- 试验地点
- 1
- 主要终点
- ATTR-CM Diagnosis
研究概览
简要总结
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a commonly undiagnosed and potentially fatal disease. Contemporary studies on this condition often underrepresent the female gender and diverse patient populations. This registry retrospectively evaluated patients referred for 99mTc-pyrophosphate (PYP) Single Photon Emission Computed Tomography (SPECT) between 2014 and 2023 at Montefiore-Einstein in the Bronx. The patient population is racially and ethnically diverse and with a high proportion of females. Demographic, clinical (e.g. comorbidities), laboratory, echocardiographic, hospitalization, and mortality data were collected for each patient.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult patients referred for PYP SPECT at Montefiore Medical Center between 2014 and 2023
排除标准
- •Did not have a transthoracic echocardiogram in our medical records
研究组 & 干预措施
Patients referred for 99mTc-pyrophosphate Single Photon Emission Computed Tomography
Patients with suspected transthyretin cardiac amyloidosis referred for 99mTc-pyrophosphate Single Photon Emission Computed Tomography
干预措施: 99mTc-pyrophosphate Single Photon Emission Computed Tomography (Diagnostic Test)
结局指标
主要结局
ATTR-CM Diagnosis
时间窗: During the index PYP scan within the study time frame parameters of the retrospective review (between 2014 and 2023)
The number of patients who underwent a PYP SPECT scan diagnostic of ATTR-CM will be assessed and reported
Mortality
时间窗: Within the study time frame parameters of the retrospective review (between 2014 and 2023)
The number of patients who died from all-cause mortality will be tabulated and reported
次要结局
- Heart failure hospitalizations(Within the study time frame parameters of the retrospective review (between 2014 and 2023))
- Total Hospitalizations(Within the study time frame parameters of the retrospective review (between 2014 and 2023))