临床试验/NCT07202260

NCT07202260进行中（未招募）不适用

Pragmatic Analysis of Complex Radiotherapy Cases In Cancer of the Lung (The PRACTICAL Study)

The Christie NHS Foundation Trust1 个研究点分布在 1 个国家目标入组 80 人开始时间: 2025年7月3日最近更新: 2025年10月1日

试验速览

阶段: 不适用
状态: 进行中（未招募）
发起方: The Christie NHS Foundation Trust
入组人数: 80
试验地点: 1
主要终点: Acute and late toxicity

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study focuses on improving care for people with lung cancer who face unusual or complex treatment situations.

详细描述

By studying detailed patient data, researchers aim to find the best ways to treat these patients while reducing short- and long-term side effects. The findings will help refine radiotherapy treatments, ensuring they are as safe and effective as possible. Additionally, the results will provide doctors with better information to help patients understand the potential risks and benefits of their treatment options.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Complex patients with lung cancer undergoing radiotherapy in one of the following groups;
•Rare histology
•Disease invading vascular structures
•Co-existing interstitial lung disease (ILD)
•Radical re-irradiation
•Oligopersistent/oligoprogressive disease on immunotherapy or targeted therapies.

排除标准

•Include patients with stage IV disease who are receiving non-curative intent radiotherapy
•There are no exclusion criteria relating to upper age limit or comorbidities.

结局指标

主要结局

Acute and late toxicity

时间窗: 2 years

\- Acute (\<90 days post radiotherapy) and late (\> 90 days post radiotherapy) toxicity according to common terminology criteria for adverse events (CTCAE) V5.

次要结局

未报告次要终点

研究者

发起方

The Christie NHS Foundation Trust

申办方类型

Other

责任方

Sponsor

研究点 (1)

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