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Intervention With a GABA Supplement in Prediabetics

Conditions
Prediabetes, hypertension
Registration Number
NL-OMON20448
Lead Sponsor
TKI funded project with industrial sponsors Nunhems, Agrico Research and Avebe
Brief Summary

n.a.

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
52
Inclusion Criteria

Age between 50 and 70
BMI higher or equal to 27 kg/m2
Impaired fasting glucose (fasting glucose = 5.6 and = 6.9 mmol/L) or/and
Impaired glucose tolerance (glucose levels = 7.8 and = 11.1 mmol/L, 2-hours after an OGTT or/and glucose levels =8.6 mmol/L, 1-hour after an OGTT)

Exclusion Criteria

Has been diagnosed with diabetes
Having other conditions, like liver, pancreatic, cardiovascular, gastro-intestinal or endocrine diseases, that could influence the study results
Use of medications or supplements that could influence the study results
Sensitive to medical skin adhesives
More than 5kg weight change in the past 12 weeks
Excessive alcohol consumption (>21 glasses/week for men and >14 glasses/week for women on average)
Being an employee of Wageningen University, division Human Nutrition and Health
Currently a research subject in other research

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postprandial glycaemic response during a 2 hour oral glucose tolerance test (OGTT)
Secondary Outcome Measures
NameTimeMethod
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