A Study of Atherosclerosis in Patients After Radiation Treatment for Breast Cancer

Completed

• Conditions: Atherosclerosis

• Registration Number: NCT00960401
• Lead Sponsor: Winthrop University Hospital

Brief Summary

The purpose of this study is to compare plaque burden in the coronary and carotid arteries 5 years after adjuvant radiotherapy in women with right sided breast cancer vs left sided breast cancer.

Detailed Description

This study reviews case series of patients with a history of breast cancer treated with radiotherapy for at least five years. The study measures atherosclerosis by using coronary and carotid artery calcium scoring.

Study Timeline

• Study Start: 2005-08
• Primary Completion: 2007-05
• Study First Submitted: 2009-08-13
• Study First Submitted QC: 2009-08-14
• Study First Posted: 2009-08-17
• Study Completion: 2014-01
• Results First Submitted: 2016-01-27
• Status Verified: 2023-02
• Results First Submitted QC: 2023-02-17
• Last Update Submitted: 2023-02-17
• Results First Posted: 2023-11-27
• Last Update Posted: 2023-11-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• women dx with ductal carcinoma in situ or breast cancer, stage 0 to stage IIIc, who received conservative surgery and radiotherapy at least 5 years ago
• less than or equal to age 60

Exclusion Criteria

• hx of coronary disease prior to tx of ductal carcinoma in situ or breast cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of Participants Analyzed for Coronary Calcium Burden by AGS	Year 5 Post-Initiation of Radiotherapy	Number of participants who received a coronary calcium scan.

Trial Locations

Locations (1)

Winthrop University Hospital; 🇺🇸 Mineola, New York, United States