In Patients With Carpal Tunnel Syndrome, Median Nerve Conduction is Evaluated After Nerve Mobilizations

Not Applicable

Not yet recruiting

• Conditions: Carpal Tunnel Syndrome
• Interventions: Other: Manual mobilizations of the median nerve; Other: Wrist movements

• Registration Number: NCT06399484
• Lead Sponsor: Universidad de Zaragoza

Brief Summary

This project is linked to the line of research on carpal tunnel syndrome, of the PhysiUZerapy research group, belonging to the University of Zaragoza. Within this line, the biomechanical and physiological effect of the proposed technique has been investigated, both in healthy subjects, in cadavers and in patients with carpal tunnel syndrome (CTS), resulting in the reading of 2 doctoral theses, the publication of 9 articles in high-impact journals. and the patent for a splint for the treatment of pathology. This project aims to provide information that is still lacking on the immediate effect of these techniques in patients with CTS. For this, there will be three groups of patients from the Lozano Blesa University Clinical Hospital distributed randomly. In two of the groups, sliding and neural tension techniques will be carried out (case group). The remaining group (control group) will be taken as a reference by performing a placebo treatment. Before and after carrying out these techniques, electrophysiological data will be collected to be able to compare them. This comparison is based on highlighting the differences between the data before the techniques and after, as well as between the case group and the control group.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-04-25
• Status Verified: 2024-05
• Study First Submitted QC: 2024-05-01
• Last Update Submitted: 2024-05-01
• Study First Posted: 2024-05-03
• Last Update Posted: 2024-05-03
• Study Start: 2024-06-15
• Primary Completion: 2024-09-15
• Study Completion: 2024-12-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Being over 18 years
• Present carpal tunnel syndrome diagnosed by electroneurogram
• Have understanding and communication skills
• Give consent to participate in the study

Exclusion Criteria

• Have received previous surgery on the hand or wrist
• Present a severe limitation of movement in any of the joints of the affected upper limb
• Not signing the informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Neural mobilization group	Manual mobilizations of the median nerve	Manual mobilizations of the median nerve.
Placebo group	Wrist movements	wrist movements no producing sliding of the median nerve

Primary Outcome Measures

Name	Time	Method
Distal motor latency (APB) (ms)	Before and immediately after the intervention
Median motor velocity (m/s)	Before and immediately after the intervention
Median sensory conduction (digit II) (13 cm) (m/sec)	Before and immediately after the intervention
Motor amplitude (APB) (mV)	Before and immediately after the intervention
Sensory amplitude (µV)	Before and immediately after the intervention

Trial Locations

Locations (1)

Hospital Clínico Universitario Lozano Blesa; 🇪🇸 Zaragoza, Spain