The prospective observational study of tissue characterization and information of genome and gene in patients with chronic thromboembolic pulmonary hypertensio
Not Applicable
Recruiting
- Conditions
- Chronic thromboembolic pulmonary hypertension
- Registration Number
- JPRN-UMIN000047520
- Lead Sponsor
- Kobe University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients suffering from hepatitis B and C viruses and human immunodeficiency virus. (2) Other patients who are deemed inappropriate by the physician in charge of the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection of single cell gene expression of the pulmonary artery intima and organized thrombus in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary endarterectomy.
- Secondary Outcome Measures
Name Time Method Relationship between various data of pulmonary artery intima and data of blood sample in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary endarterectomy. 1. bulk RNA sequencing 2. exosome analysis 3. histological evaluation 4. single cell ATAC sequencing 5. single cell RNA sequencing of blood sample 6. exosome analysis of blood sample