The Effect of Refractive Errors on Central Corneal Thickness by Using Pentacam and IOL Master

Not yet recruiting

• Conditions: Central Corneal Thickness
• Interventions: Device: Pentacam and IOL master

• Registration Number: NCT06484894
• Lead Sponsor: Assiut University

Brief Summary

To evaluate the impact of refractive errors on the central corneal thickness obtained by Pentacam and intraocular lenses (IOL) master in eyes with different refractive errors.

Detailed Description

Central corneal thickness (CCT) is a key indicator of corneal health status and helps to assess corneal diseases. The normal corneal thickness is about 540 μm and mainly consists of the stroma, which is estimated at 450 μm in the center. The stroma provides vital structural integrity and plays a key role in helping maintain transparency. It has been reported, however, that CCT follows a diurnal pattern being 10 μm thicker in the morning due to reduced evaporation of water from underneath the closed eyelids

Study Timeline

• Status Verified: 2024-06
• Study First Submitted: 2024-06-26
• Study First Submitted QC: 2024-06-26
• Last Update Submitted: 2024-06-26
• Study First Posted: 2024-07-03
• Last Update Posted: 2024-07-03
• Study Start: 2024-07-15
• Primary Completion: 2025-07
• Study Completion: 2025-08

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Subjects included in this study aged between20 and 41 years, asked for refractive surgery

Exclusion Criteria

• patients with corneal scarrig or opacification.

  • Patients with corneal dystrophies.
  • Patients with keratoconus.
  • Previous ocular or refractive surgery.
  • Ocular trauma.
  • Uveitis patients.
  • Patients with history of recent contact lens wear.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Hypermetrope	Pentacam and IOL master	Effect of hypermetropia on central corneal thickness by using pentacam and IOL master
Emmetrope	Pentacam and IOL master	Effect of emmetropia on central corneal thickness by using pentacam and IOL master
Myopia	Pentacam and IOL master	Effect of myopia on central corneal thickness by using pentacam and IOL master

Primary Outcome Measures

Name	Time	Method
To find if there a correlation between refractive errors and the central corneal thickness	Baseline	Study the effect of refractive errors on central corneal thickness

Secondary Outcome Measures

Name	Time	Method
To study if there a difference between measurement by pentacam and measurement of IOL master	Baseline	Study which device is more accurate in measuring the central corneal thickness and if there is any difference between the two devices