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Evaluation of a home-based prehabilitation program for high-risk patients undergoing major elective abdominal surgery: a one-group pre-test post-test pilot study.

Withdrawn
Conditions
Tumoren in darm, lever of pancreas waarvoor resectie gepland is
Colorectal cancer
hepatic cancer
pancreatic cancer
10027656
10019190
Registration Number
NL-OMON48744
Lead Sponsor
Medisch Universitair Ziekenhuis Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Withdrawn
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

- More that 18 years of age;
- Scheduled for elective colorectal, hepatic, or pancreatic resection at Maastricht UMC+;
- A low physical fitness according to the preoperative screening with the advice to participate in the hospital's prehabilitation program (usual care);
- Willing to participate in the hospital's prehabilitation program (usual care);
- Providing informed consent to participate;
- After informed consent, classified as being at risk for a complicated postoperative period (VAT *11 mL/kg/min at the pre-prehabilitation CPET).

Exclusion Criteria

- Patients requiring acute (emergency) surgery;
- Patients undergoing surgery in another hospital than Maastricht UMC+;
- Patients with contraindications for physical exercise training;
- Unable to cooperate with the testing procedures (e.g., insufficient understanding of the Dutch language).

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The main study parameter is the feasibility (adherence/compliance, adverse<br /><br>events, and patient appreciation) of a four-week home-based prehabilitation<br /><br>program in individual high-risk patients scheduled for elective colorectal,<br /><br>hepatic, or pancreatic resection.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary parameters are to explore:<br /><br>1) individual responses to the program (physical fitness),<br /><br>2) changes in immune system activity,<br /><br>3) changes in nutritional status,<br /><br>4) changes in quality of life,<br /><br>5) changes in health status, and<br /><br>6) short-term postoperative outcomes (e.g., and time to recovery of physical<br /><br>functioning, 30-day morbidity). </p><br>
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