Study of Neutrophils and Circulating Platelets in Correlation With the Activity of T Lymphocytes in Patients With NAFLD (Nonalcoholic Fatty Liver Disease)
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- number of Neutrophilis
研究概览
简要总结
The aim of the study is to define the relationship between neutrophils, platelets and the activity of T lymphocytes in patients with NAFLD (nonalcoholic fatty liver disease).
This study may predict, in the course of hepatic steatosis, specific phenotypic patterns expressed by PMNs and circulating platelets to evaluate their role in disease progression.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients over 18
- •No alcoholic abuse
- •Hepatic steatosis diagnosticated by abdominal ultrasound
- •Negative hepatitis B and C tests
- •No history of hepatic cirrhosis
排除标准
- •History of alcoholic abuse
- •Positive serology for hepatitis B or C
- •History of hepatic cirrhosis
结局指标
主要结局
number of Neutrophilis
时间窗: 12 months
Morphology of Circulating Platelets in healthy donors, NAFL, and NASH patients wondering how they may drive and modulate the activity of T cells in this disease
时间窗: 12 months
Morphology of Neutrophilis
时间窗: 12 months
IL-8(interleukin 8)
时间窗: 12 months
Platelets count in healthy donors, NAFL, and NASH patients
时间窗: 12 months
次要结局
未报告次要终点
研究者
Clara Balsano
Full Professor
University of L'Aquila