Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurosurgical Intensive Care Unit

Not Applicable

• Conditions: Thromboses, Venous; Infection; Economic Problems
• Interventions: Other: CVC(Central venous catheter ); Other: PICC(Peripherally inserted central catheter)

• Registration Number: NCT03908866
• Lead Sponsor: First Affiliated Hospital Xi'an Jiaotong University

Brief Summary

This study aim to compare the cost-effectiveness and safety between centrally and peripherally inserted central venous catheters in neurosurgical intensive care unit patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-04
• Study Start: 2019-04-01
• Study First Submitted: 2019-04-07
• Study First Submitted QC: 2019-04-08
• Study First Posted: 2019-04-09
• Last Update Submitted: 2019-04-21
• Last Update Posted: 2019-04-23
• Primary Completion: 2019-12-31
• Study Completion: 2019-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Adult patients admitted to the neurosurgical intensive care unit , who require central access for the treatment of their illness.

Exclusion Criteria

• Insertion of the central catheter in emergency situations;
• Anatomical abnormalities of upper extremity affecting PICC placement;
• Current or recent (within 1 month) diagnosis of bacteremia
• Current or recent (within 1 year with confirmed resolution by imaging) deep venous thrombosis;
• Presence of skin changes in the area of the puncture, such as thrombophlebitis, dermatitis, cellulitis, burn among others;

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CVC(Central venous catheter )	CVC(Central venous catheter )	Patients randomly assigned to receive a centrally inserted central venous catheter(CVC).
PICC(Peripherally inserted central catheter)	PICC(Peripherally inserted central catheter)	Patients randomly assigned to receive a peripherally inserted central catheter(PICC).

Primary Outcome Measures

Name	Time	Method
infectious complications	up to 30 days or be discharged from hospital	catheter related bloodstream infection
thrombotic complications	up to 30 days or be discharged from hospital	radiographically-confirmed upper-extremity deep vein thrombosis
mechanical complications	up to 30 days or be discharged from hospital	pneumothorax or hematoma caused by puncture

Secondary Outcome Measures

Name	Time	Method
catheter replacement	up to 30 days or be discharged from hospital	obstruction or accidental removal
cost effectiveness	up to 30 days or be discharged from hospital	The cost of catheter implantation and replacement, as well as the cost of treatment due to catheter-related complications and the resulting financial loss to the patient.

Trial Locations

Locations (1)

First Affiliated Hospital of Xian Jiaotong University; 🇨🇳 Xi'an, Shaanxi, China