Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes

Completed

• Conditions: Renal Replacement Therapy; Mortality
• Interventions: Other: Nephrologist referral

• Registration Number: NCT01151514
• Lead Sponsor: Centre Hospitalier Universitaire Vaudois

Brief Summary

Few studies analyzed the referral time to nephrologists and its impact on the patient outcome in a large cohort. The investigators described the incidence and determined the outcome with respect to renal function recovery, renal replacement therapy (RRT) requirement and in-hospital mortality of Hospital Acquired Acute Kidney Injury (HA-AKI) without nephrology referral (nrHA-AKI) and late referred HA-AKI patients to nephrologists (lrHA-AKI) compared with early referral patients (erHA-AKI). The patients included were admitted to the tertiary care academic center of Lausanne (Switzerland) between 2004 and 2008, in the medical and surgical services and in the intensive care unit (ICU).

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-06-23
• Study First Submitted QC: 2010-06-25
• Last Update Submitted: 2010-06-25
• Study First Posted: 2010-06-28
• Last Update Posted: 2010-06-28
• Status Verified: 2010-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Adult patients.
• Hospitalization in the medicine and surgery wards and in the intensive care unit.
• Hospitalized patients with acquired acute kidney injury according to the
• Acute Kidney Injury Network (AKIN)criteria.
• HA-AKI patients with no referral to the nephrologist (nrHA-AKI).
• HA-AKI patients referred late (more than five days [> 5 days]) to the nephrologist (lrHA-AKI).
• HA-AKI patients early referred (within five days after sCr increase) to the nephrologist (erHA-AKI).

Exclusion Criteria

• Patients with AKI at the time of the hospital admission and during the first
• 48 hours after admission.
• Patients hospitalized in other wards.
• Children under 18.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
nrHA-AKI patients	Nephrologist referral	Patients with hospital-acquired acute kidney injury not referred to the nephrologists
lrHA-AKI patients	Nephrologist referral	Patients with hospital-acquired acute kidney injury whao are late referred to the nephrologists

Primary Outcome Measures

Name	Time	Method
Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes		Recovery of renal function during hospital stay. Requirement for renal replacement therapy.

Secondary Outcome Measures

Name	Time	Method
Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes		Length of hospital stay. In-hospital mortality.

Trial Locations

Locations (1)

Nephrology - CHCVs; 🇨🇭 Sion, Switzerland