MedPath

Day-case stapes surgery compared to in-patient surgery in patients with otosclerosis.

Conditions
Otosclerosis (in Dutch: otosclerose).
Registration Number
NL-OMON29237
Lead Sponsor
niversity Medical Centre Utrecht
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
112
Inclusion Criteria

• Age ≥ 18;

• Otosclerosis based on a clinical history of progressive hearing loss and pure-tone audiometry showing conductive hearing loss with an air-bone gap > 20 dB nHL and a perceptive hearing loss < 35 dB nHL in the range of 500, 1000, 2000 and 4000 Hz;

Exclusion Criteria

• Previous middle ear surgery (other than previous stapes surgery);

• Known aberrant (middle ear) anatomy in one or both ears;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postoperative air conduction on pure-tone audiometry at 12 months follow-up.
Secondary Outcome Measures
NameTimeMethod
- Performance on pure-tone audiometry (mean air-bone gap, bone conduction thresholds, air conduction thresholds);<br>- Performance on speech audiometry;<br>- General and disease-specific quality of life<br>- Tinnitus;<br>- Vertigo;<br>- Use of escape medication;<br>- Intraoperative and postoperative complications;<br>- Cost-utility analysis.
© Copyright 2025. All Rights Reserved by MedPath