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Day-case versus in-patient stapes surgery for otosclerosis: a randomized controlled trial.

Completed
Conditions
ossification
otosclerosis
10027584
Registration Number
NL-OMON44763
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
112
Inclusion Criteria

Age >= 18;
Otosclerosis based on a clinical history of progressive hearing loss and pure-tone audiometry showing conductive hearing loss with an air-bone gap > 20 dB nHL in the range of 500, 1,000, 2,000 and 4,000 Hz;
Willingness and ability to participate in all scheduled procedures outlined in the research protocol;
General health allowing general anesthesia;
Quick access to communication and transportation in case of any complications;
Good understanding of the Dutch language.

Exclusion Criteria

Previous middle ear surgery other than stapes surgery;
Aberrant (middle ear) anatomy in one or both ears;
Co-morbid middle or inner ear pathology, osteogenesis imperfecta or an active ear infection in one or both ears;
Disability that could interfere with audiologic evaluation and/or questionnaire fulfillment.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary outcome measure is postoperative air conduction on pure-tone audiometry<br /><br>at 12 months follow-up. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary outcome measures are hearing improvement on pure-tone and speech<br /><br>audiometry, disease-specific and general quality of life, tinnitus, vertigo,<br /><br>cost-effectiveness and complications. </p><br>
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